Regu-Mate is an oral progestin indicated for the suppression of the estrus cycle (reproductive cycle) in mares (female horses). The suppression of the estrus cycle allows for a predictable occurrence of estrus following drug withdrawal. It keeps your mare's cycle regular during the transition from winter anestrus to the physiological breeding season. Regu-Mate helps manage prolonged estrus conditions and helps you schedule breeding during the physiological breeding season. Regu-Mate requires a prescription from your veterinarian.